Sunday, April 11, 2010

Mushrooms and Science

When I was young, there was a homeless man in the park who started to think he was an orange after indulging in too many psycheledelics. It was a cautionary story. We all knew that overindulgence could lead to the average person quitting Pink Floyd at the first beckoning of fame and then retreating to the British countryside to chew your hand and live with your mom. That was all a fate we all wanted to avoid.




Nevertheless, you knew something was up with mushrooms. They were just far too strong and powerful. For all the industrial waste churned out like tie-dye and Timothy Leary; there had to be something scientists could do to make it respectable, cold, bureaucratic but useful. And perhaps they have ...


Hallucinogens Have Doctors Tuning In Again
By
JOHN TIERNEY
Published: April 11, 2010
As a retired clinical psychologist, Clark Martin was well acquainted with traditional treatments for
depression, but his own case seemed untreatable as he struggled through chemotherapy and other grueling regimens for kidney cancer. Counseling seemed futile to him. So did the antidepressant pills he tried.
Nothing had any lasting effect until, at the age of 65, he had his first psychedelic experience. He left his home in Vancouver, Wash., to take part in an experiment at Johns Hopkins medical school involving psilocybin, the psychoactive ingredient found in certain mushrooms.
Scientists are taking a new look at hallucinogens, which became taboo among regulators after enthusiasts like Timothy Leary promoted them in the 1960s with the slogan “Turn on, tune in, drop out.” Now, using rigorous protocols and safeguards, scientists have won permission to study once again the drugs’ potential for treating mental problems and illuminating the nature of consciousness.
After taking the hallucinogen, Dr. Martin put on an eye mask and headphones, and lay on a couch listening to classical music as he contemplated the universe.
“All of a sudden, everything familiar started evaporating,” he recalled. “Imagine you fall off a boat out in the open ocean, and you turn around, and the boat is gone. And then the water’s gone. And then you’re gone.”
Today, more than a year later, Dr. Martin credits that six-hour experience with helping him overcome his depression and profoundly transforming his relationships with his daughter and friends. He ranks it among the most meaningful events of his life, which makes him a fairly typical member of a growing club of experimental subjects.
Scientists are especially intrigued by the similarities between hallucinogenic experiences and the life-changing revelations reported throughout history by religious mystics and those who meditate. These similarities have been identified in neural imaging studies conducted by Swiss researchers and in experiments led by Roland Griffiths, a professor of behavioral biology at Johns Hopkins.
In one of Dr. Griffiths’s first studies, involving 36 people with no serious physical or emotional problems, he and colleagues found that psilocybin could induce what the experimental subjects described as a profound spiritual experience with lasting positive effects for most of them. None had had any previous experience with hallucinogens, and none were even sure what drug was being administered. The monitors sometimes had to console people through periods of anxiety, but these were generally short-lived, and none of the people reported any serious negative effects. In a survey conducted two months later, the people who received psilocybin reported significantly more improvements in their general feelings and behavior than did the members of the control group.
After 14 months, most of the psilocybin subjects once again expressed more satisfaction with their lives and rated the experience as one of the five most meaningful events of their lives.
Dr. Martin’s experience is fairly typical, an improved outlook on life after an experience in which the boundaries between the self and others disappear.
Dr. Martin and other subjects described their egos and bodies vanishing as they felt part of some larger state of consciousness in which their personal worries and insecurities vanished. They found themselves reviewing past relationships with lovers and relatives with a new sense of empathy.
“It was a whole personality shift for me,” Dr. Martin said. “I wasn’t any longer attached to my performance and trying to control things. I could see that the really good things in life will happen if you just show up and share your natural enthusiasms with people. You have a feeling of attunement with other people.”
The subjects’ reports mirrored so closely the accounts of religious mystical experiences, Dr. Griffiths said, that it seems likely the human brain is wired to undergo these “unitive” experiences, perhaps because of some evolutionary advantage.
“There’s this coming together of science and spirituality,” said Rick Doblin, the executive director of MAPS. “We’re hoping that the mainstream and the psychedelic community can meet in the middle and avoid another culture war. Thanks to changes over the last 40 years in the social acceptance of the hospice movement and yoga and meditation, our culture is much more receptive now, and we’re showing that these drugs can provide benefits that current treatments can’t.”
Researchers are reporting preliminary success in using psilocybin to ease the anxiety of patients with terminal illnesses.
Dr. Charles S. Grob, a psychiatrist who is involved in an experiment at U.C.L.A., describes it as “existential medicine” that helps dying people overcome fear, panic and depression.
“Under the influences of hallucinogens,” Dr. Grob writes, “individuals transcend their primary identification with their bodies and experience ego-free states before the time of their actual physical demise, and return with a new perspective and profound acceptance of the life constant: change.”



Possible Equation(s):
Psychedelics + Mature age + Depression + Controlled Bureaucratic Circumstance - minus California = Happiness
Psychedelics + California + Jesus Freaks - Maturity (or Job) divided by the number of times you halucinate without psychedelics X multiplied by the amount of New Riders of the Purple Sage Concerts (NRPoS) attended = Joining the Manson Family Becoming An Orange
Two Possible Results:
Psychedelics are wasted on the young.
Timothy Leary and his pseudoscience were the actual worst possible things for the expansion of the use of psychedelics.












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